Thus, we hypothesized that GLP-1R might participate in the regulation of PKA/CREB signals, which are likely to be involved in inflammatory processes
This is the central problem with oral GLP-1s, then
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The results were consistent with the overall SELECT trial findings and showed a numerically larger risk reduction in the perimenopausal women (42% lower risk compared to placebo) compared to the postmenopausal women (13% lower risk compared to placebo), although the difference between the groups was not statistically significant
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Five-year tumour recurrence was also statistically significantly reduced, with 79%, 51%, and 31% recurrence in the 1-9, 10-15, and 16 NLN groups, respectively (Log-rank = 9.24, p = .001)