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Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

I reserve stacking for severe injuries, post-surgical recovery, or cases where initial BPC-157 treatment produced only partial improvement

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Clients may notice a mild, harmless yellow tint in urine for several hours as excess water-soluble B12 is excreted