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Losken, Daniel J Gould Journal: Aesthetic Surgery Journal
This matters for the meniscus specifically because the white-zone tear creates a local hypoxic pocket
Since nitrous oxide is commonly used for surgery in the elderly, some experts feel vitamin B 12 deficiency should be ruled out prior to its use or prophylactic vitamin B 12 supplementation implemented before and after exposure to the gas (7, 18)
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Clinical data is sparse and inconsistent
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