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The use of semaglutide is not yet approved in children under 12 years of age, and geriatric use in sensitive populations is relatively lacking in safety data [9]

Patients with rheumatoid arthritis who are considering semaglutide or other GLP-1 agonists must consult their rheumatologist to ensure coordination of care and to rule out contraindications

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In one study, 12-week treatment with insulin glargine vs liraglutide (mean dose = 1.3 mg/day) showed similar glycemic control and decrease of hepatic fat burden, although a reduction in BMI was only observed in the liraglutide-treated patients (68)

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