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Lower the risk of major cardiovascular events such as heart attack and stroke and cardiovascular death in adults with known heart disease and either obesity or overweight, alongside diet and exercise

Specifically, this type of diet restriction promoted a significant decrease in the relative abundance of multiple Ruminococcaceae and Prevotellaceae families while increasing the presence of members of the Lactobacillaceae family

Understanding how these sweeteners affect GLP-1, CCK, PYY, and ghrelin secretion can provide insights into their potential benefits for weight management and metabolic health 2

It may also raise the risk of other heart and blood vessel problems

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It should also be noted that during our study period, semaglutide was reported to exhibit both the highest weight-reducing effect [5, 18] and reduction of glycemia [6], which could be a contributory factor to the increase in the use of this substance in particular