Large-scale meta-studies also indicate that women are slightly more prone to IBS than men and that people aged 20-40 are mainly affected, with prevalence decreasing beyond this age
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In addition, PEGylation reduces the clearance of protein drugs by reticuloendothelial tissue, shields antigenic determinants, reduces immune system recognition, and prevents degradation by proteolytic enzymes
However, at certain times, they can cause side effects
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