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Think of it as less goes in, less comes out. Fewer bowel movements can be normal ( even as few as three per week ), but experiencing hard stool, difficulty passing stool, bloating, abdominal pain, or incomplete evacuation would be considered constipation

There are other benefits of tirzepatide beyond diabetes and obesity, as evidence has been published on heart failure with preserved ejection fraction and obstructive sleep apnea

Peptide YY and proglucagon mRNA expression patterns and regulation in the gut

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FDA Prescribing Information Mounjaro (Tirzepatide) injection Prescribing Information

For more details, read our guide on using HSA for GLP-1 medications and FSA eligibility for GLP-1 treatments