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CCK-8 assay indicated that macrophage viability significantly decreased at silica concentrations greater than 50 g/cm 2 (Fig
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PMID: 65 JelenikT.KaulK.SequarisG.FlogelU.PhielixE.KotzkaJ.et al
Biochem J 1:2838
Overexpression of CBS also has the downstream effect of increasing cysteine availability and the potential for a functional folic acid deficiency known as the folate trap in DS individuals (Pogribna et al , 2001)
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