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These need prompt medical attention

Timing Baseline Marker CRP Why it matters Can provide a general inflammation trend, although it does not show whether a local tendon or ligament is healing

Aging (Milano), 12 , 199207

A variety of cellular stresses, including DNA damage can cause the induction of cellular senescence, which represents a multifaceted and highly heterogeneous cellular state characterized by irreversible growth arrest and importantly the secretion of a multitude of factors, including proteases and chemokines 2

Freezing can cause the peptide molecules to aggregate irreversibly, meaning they clump together and cannot be separated again

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