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10.1007/s00125-010-1937-z 84 MannucciE.TesiF.BardiniG.OgnibeneA.PetraccaM

Experiments with some animal models have revealed that TMAO reduces blood pressure and plasma levels of NT-proBNP in rats and also inflates the left ventricular ejection fraction (LVEF).TMAO has a protein-stabilizing effect and promotes heavy plasmin and actin complexes, increasing myocardial contractility in humans and mice

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Another key benefit is its role in supporting liver health