For instance, studies in germ-free or antibiotic-treated mouse and rhesus monkey models have demonstrated reduced levels of BBB tight junction proteins (e.g., claudin-5, occludin) and increased BBB permeability
Green tea extract, turmeric, and moringa leaf extract are rich in powerful antioxidants and anti-inflammatory compounds that protect the skin from oxidative stress and environmental damage, helping slow down the aging process
This makes it particularly relevant in clinical contexts where someone has gut lining compromise alongside systemic inflammation, for example, long-term NSAID use for chronic pain
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10.2174/157339706776876017 Ekmekcioglu C, Strauss-Blasche G, Holzer F, Marktl W: Effect of sulfur baths on antioxidative defense systems, peroxide concentrations and lipid levels in patients with degenerative osteoarthritis