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Perturbation of iron homeostasis leads to elevated levels of intracellular free ferrous iron, which reacts with peroxides to produce ferric ions and peroxyl radicals, consequently resulting in a substantial increase in ROS production [86]

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This is because reducing inflammation doesnt directly inhibit 5-alpha reductase, but rather, inhibits the inflammation that signals 5-alpha reductase to arrive in certain tissues (like our scalp skin and prostates)

Finally, in dispersion, bacteria are released from the biofilm and return to the planktonic state to colonize new sites

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doi: 10.1016/j.phrs.2021.105437