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Tirzepatide is engineered as an imbalanced agonist in terms of its strong affinity and potency at the GIPR versus the GLP-1R
indeed, severe deficiencies of B vitamins are a known danger to pregnancy, whereas supplementing them is generally beneficial
While improvements in diet and physical activity might explain some of the overall improvement, they do not account for the differences observed between the active and placebo groups
Pathol Res Pract 270: 155985
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