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Oral supplementation has lower bioavailability than injectable forms but may produce more TMAO due to gut bacteria exposure

The recommended injection sites include the abdomen (at least two inches from the belly button), the front of the thighs, and the back of the upper arms

Human growth hormone (hGH) is produced by the pituitary gland

People with severe gastrointestinal (GI) disorders, such as gastroparesis or inflammatory bowel disease, should also avoid GLP-1 agonists due to the possibility of exacerbating GI symptoms (23)

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GLP-1 also signals appetite centers in the brain, indicating a sense of fullness during and between meals by slowing gastric emptying