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Absorption from an intramuscular dose has been measured between 55% and 97%

While the injections can indeed improve energy levels in those with a deficiency, it is essential to note that they are unlikely to provide significant benefits for individuals with normal B12 levels

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Severe Infantile vitamin B12 deficiency significantly impairs head growth, overall development, and body composition (263)

This direct administration is particularly beneficial for individuals with malabsorption issues, such as those with pernicious anemia, Crohn's disease, or celiac disease

The patients comfort level, age, sex, physique, and health goals may also determine the injection location