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This research is supported by grants from the National Science and Technology Council, Taiwan (NSTC 112-2326-B-002-006 and NSTC 1122320-B-002-005)
K., Streu, C
For the analysis of trial duration, the absolute value of weight change was significantly higher in the long-term group than that the short-term group
The genes affected by semaglutide included markers of inflammation and plaque stability that are associated with leukocyte recruitment [e.g., interleukin-1 (IL-1) receptor antagonist, IL-6, monocyte chemoattractant protein (CCL2), OPN], leukocyte adhesion [selectin E, vascular cell adhesion molecule-1 (VCAM1)], leukocyte extravasation and plaque stability (e.g., MMP3, MMP13, CCL2), and plaque rupture and hemorrhage (CD163)
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