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It will also be important to determine whether these drugs can be used in combination with other therapies to optimize the treatment of HFpEF in obese patients, while minimizing side effects and drug interactions
If the diarrhea persists, reduction of dose or discontinuing of use is recommended
Caloric deficit and nutritional inadequacy represent a common cause of fatigue
Additionally, adequate sleep (typically 69 hours nightly for adults, per NHS guidance) and stress management support hormonal balance, including optimal GLP-1 function, as chronic stress and sleep deprivation can impair incretin responses
If youve decided to end your GLP-1 journey, its important to understand the physical, mental, and emotional implications to ensure youre setting yourself up for success
Griffin et al., 2022
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