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During clinical trials, melanotan II consistently produced spontaneous erections and increased sexual desire in male subjects a side effect significant enough to warrant development of a dedicated compound

Importantly, current studies have not shown any negative effects of GLP-1 therapy on sperm count or sexual function

Semaglutide won't lead to lower blood sugar or weight loss from weekly injections alone

Many people take one of these injections alongside metformin, and the main head-to-head trials were done in people already using metformin

For instance, while Semaglutide may lead to noticeable weight loss and glycemic improvements within weeks, the full benefits of antidepressants like Zoloft might not manifest until 4-6 weeks into the treatment