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Clinical characteristics, treatment patterns, and persistence in individuals with type 2 diabetes initiating a glucagon-like peptide-1 receptor agonist: a retrospective analysis of the Diabetes Prospective Follow-Up Registry

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The secondary end points were AMG 133 PK parameters, including t max and t 1/2

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The gradual dose-escalation approach used with these medications serves to minimize gastrointestinal side effects while achieving therapeutic goals

Future studies should conduct patient-data-based or refined network meta-analyses of different GLP-1 RAs, doses, and MASLD populations with or without T2DM to distinguish their efficacy and safety