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Further, the FDA-approved synthetic peptide bremelanotide, which is a naturally-occurring metabolite of MT-II, has been evaluated in clinical trials in a nasal spray format [31]

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Thus, reduction of oxidative stress by interventions could be a potential approach to mitigate obesity-induced sperm and testicular oxidative damage and associated programming

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Diabetes Obes Metab 2010;12:48594

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