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B12 injections may boost your energy levels and mood, especially if you have a B12 deficiency

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Start with lower concentrations and frequency

Eli Lilly published the results of its ATTAIN-1b trial for obesity in September 2025 7 , which compared orforglipron to placebo in more than 3,100 adults without diabetes, with a BMI of 30+ or 27-30 with an obesity-related complication including hypertension, dyslipidaemia, cardiovascular disease or obstructive sleep apnoea and a history of at least one patient-reported unsuccessful dietary effort to lose body weight, who have tried unsuccessfully to lose weight with diet alone

The team at ThinWorks can help you decide whether oral, sublingual, or injectable B12 makes the most sense given your digestion and lab results. Why Vitamin B12 Is So Important Low levels of vitamin B12 can have an impact on everything from energy to brain health because it is essential for the production of red blood cells, nerve function, and DNA synthesis