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Biochem Pharmacol 34:11851189

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Inclusion criteria required participants to be over age 18, read and speak English, have a Hoehn & Yahr score between 2 and 3 (bilateral disease, not severely disabled), and have three or more of the required positive criteria for the diagnosis of definite PD from Step 3 of the UK Brain Bank Diagnostic Criteria for PD

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Acne and inflammation often leave behind dark marks, while hormonal changes may deepen the pigmentation on the skin