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Maganti K, Onyemere K, Jones MP
However, weight change on the scale may lag behind appetite changes by 12 weeks due to fluid shifts and normal daily fluctuations, so appetite cues are often a better early indicator than daily weigh-ins
Phase 2 trial data (Jastreboff et al., NEJM, 2023) demonstrated substantial weight reduction participants lost a mean of approximately 24% of body weight over 48 weeks at the highest doses alongside improvements in cardiometabolic markers
Yet, since it is only available from animal protein, such as red meat (particularly beef), seafood, other meats, and dairy products, this means vegetarians, especially vegans who eat no animal protein, are at particularly high risk for a functional deficiency
The authors are affiliated with the College of AI, Cyber and Computing at UT San Antonio and the South Texas Poison Center, Department of Emergency Medicine, Long School of Medicine at UT San Antonio
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