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GSH depletion is a common feature of DD triggered by a wide variety of cause including disturbance in GSH homeostasis and modification of the GSH related enzymes

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MWPC threshold for the SF-36v2 physical functioning domain was empirically derived to be 5.76 (norm based)

Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells