surmount 5 tirzepatide surmount-1 weight loss nondiabetic non-diabetic obesity trial For the first time, and semaglutide were put in the same trial. SURMOUNT-5. Phase 3b RCT. 751 adults Tirzepatide after intensive lifestyle intervention – From SURMOUNT-5, some quotes/data points/graphs

They take menopause symptoms into account and personalize medications accordingly

water injected slowly down the inside vial wall, not onto the lyophilized cake (which protects the peptide structure)

Rotate with every dose: DailyMed label requires rotating injection sites each weekly injection Avoid damaged skin: Do not inject into tender, bruised, damaged, or scarred skin within any approved zone Investigational status: Retatrutide has no FDA-approved IFU yet

There was an even split of male and female participants, the median treatment duration was 66 weeks, and the baseline systolic blood pressure was 128 millimeters of mercury (mm Hg)

Why are so many people suddenly promoting them

Someone with Crohn's disease might not tolerate standard tirzepatide doses due to GI side effects, but might tolerate microdoses that still provide some anti-inflammatory benefit