When Yuyang Liu, a graduate student in his lab and first author of the study, compared SLC25A39s structure against others in the SLC family of transporters in the AlphaFold protein structure database, Liu spotted a unique extra loop in the protein
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OxLDL components and their interaction with toll-like receptors (TLRs) 2 and 4, CD36 and other cellular receptors further mediate thromboinflammation enhancing tissue and organ damage culminating in organ failure, i.e., myocardial infarction, stroke, and pulmonary artery embolism (174, 209212)
Breast Cancer Res Treat
Andreeff M , Beck JD, Kapoor N, Steinmetz J, Melamed MR, Gee T, Miller D, Clarkson B
Nature , 432(7016), 466472