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Tirzepatide has the potential benefit of improving metabolic control and cardiovascular function because of its dual activity on GIP and GLP-1 receptors

Patients in large clinical trials for GLP-1s lost an average of 15% to 20% of their body weight, depending on the drug they were given

While multiple clinical trials and population-based studies have established the safety profile of GLP-1RAs, continued vigilance regarding the association between GLP-1RA therapy and pancreatic cancer risk remains imperative in clinical practice, given the potential for low-grade chronic pancreatitis to induce pancreatic cancer

Cloos, J

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The Gila Monster and its allies: the relationships, habits, and behavior of the lizards of the Family Helodermatidae