Taste disturbances (dysgeusia) are documented in the tirzepatide SmPC and can manifest as a metallic taste, altered flavour perception, or general taste changes that patients may associate with tongue discomfort
This landmark decision reflects the growing body of evidence linking GLP-1 medications to improved outcomes for sleep apnea patients, particularly through weight loss and other metabolic benefits
In South Africa these medicines are given as once-weekly or daily injections using pre-filled pens
FAERS database includes the following eight types of files: demographic and administrative information (DEMO), drug information (DRUG), adverse events (REAC), patient outcomes (OUTC), report sources (RPSR), start and end dates for reported drugs (THER), indications for use (INDI), and invalid reports (DELETED)
The key features that distinguish paraptosis from classical apoptosis include its independence from caspase-9 activation, the absence of typical apoptotic markers such as chromatin condensation or DNA laddering, and cytoplasmic vacuolisation as the predominant morphological feature positively modulated by the mitogen-activated protein kinase (MAPK) signalling pathway [119]
doi: 10.1530/acta.0.115S007 129 GaboritBJullaJ-BBesbesSProustMVincentelliCAlosBet al