Wharton S, Davies M, Dicker D, Lingvay I, Mosenzon O, Rubino DM et al (2022) Managing the gastrointestinal side effects of GLP-1 receptor agonists in obesity: recommendations for clinical practice
The reason is straightforward: tendons and ligaments have poor native blood supply, which means they heal slowly under the best circumstances and often stop progressing entirely after initial recovery
So, taking them for aesthetic reasons is plain dangerous
Vitamin B12 deficiency. SW London Integrated Medicines Optimisation Committee

Across major trials: Lean mass typically represents 2540% of total weight lost , meaning 6075% is fat loss . Imaging studies suggest tirzepatide may improve muscle quality , reducing fat infiltration within muscle tissueeven as total lean mass declines. A prospective 12-month semaglutide study demonstrated favorable body-composition changes with preserved or improved functional outcomes in some participants. In short: body composition improves , even when the scale shows lean-mass reduction. Muscle Changes by Weight-Loss Method How to Preserve Muscle on Semaglutide or Tirzepatide Protein targets for GLP-1 patients A clinically supported target for preserving lean mass during weight loss is: 1.21.6 g/kg/day ( 0.540.73 g/lb/day ) for most adults Higher intakes approximately 0.71.0 g per pound of body weight per day may be beneficial for individuals performing regular resistance training, particularly during calorie restriction, to better preserve or increase lean mass. Distributing protein across meals (often ~2540 g per meal ) supports muscle protein synthesis. Resistance training 23 per week Resistance training provides the mechanical signal required to retain muscle.

Goop this is not, at least not in its aesthetic, though a comparison is apt