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Chemical Information: Molecular Formula: CHO Molecular Weight: 108.14 g/mol CAS Number: 100-51-6 Purity: 99% Product Characteristics: Volume: 10mL Composition: Sterile water containing 0.9% benzyl alcohol Purpose: Solvent/diluent for peptide reconstitution and laboratory research Multi-use vial: Designed for multiple withdrawals under aseptic conditions Intended Use: For laboratory research purposes only
W.ThronT.JanssenS.ShastriG
101136670, IMI-OPTIMA no
The non-labeled peptide was added at increasing concentrations to a fixed concentration of FITC-labeled peptide (510 nM final concentration, depending on the protein) and protein of interest
The study confirmed FOXO4-DRI was effective across senescent cells generated by different methods (irradiation, doxorubicin, and replication stress), and documented that pre-treatment with FOXO4-DRI attenuated the dedifferentiation of chondrocytes during in vitro expansion establishing it as a valuable tool for research into senescent cell biology in cartilage and musculoskeletal models
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