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eccDNA have been found in classical model organisms like yeast (Mller et al., 2015b), Drosophila (Stanfield and Helinski, 1976), frogs ( Magnaporthe oryzae (Joubert and Krasileva, 2022), as well as from a variety of non-model organisms like boar (Hotta and Bassel, 1965) and pigeons (Mller et al., 2020)

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Concurrently, certain probiotics are capable of endogenously producing SCFAs, directly contributing to epigenetic regulation

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