NICE guidance on obesity management emphasises the importance of individualised treatment plans that consider comorbidities and patient preferences
Of the estimated 2 million Americans with opioid use disorder, its unclear how many also have diabetes or weight-related conditions that could prompt them to seek GLP-1s and, given the medications price tag, how many could access them, even if they were interested
Same goes for MOTS-C, which is currently in an ongoing Phase 2a clinical trial evaluating its effects on insulin sensitivity in adults with prediabetes and obesity
As obesity is a key risk factor for type 2 diabetes, cardiovascular disease, and other metabolic disorders, effective pharmacological interventions are increasingly sought after
Imamura, M
While no medication is without risks, semaglutide has a strong safety record when used under proper medical supervision