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(PubMed) Amenyah SD, Ward M, McMahon A, et al
In chemotherapy-sensitive patients, Keap1 (Kelch-like ECH-associated protein 1) binds to NRF2 and mediates NRF2 ubiquitination via the Cul3-E3 ligase complex, promoting its degradation and maintaining NRF2 at low levels [32]
Thomas MC
Authors have reported mild and temporary skin reactions at the injection site, such as redness, itching, or swelling
No clinical trial has tested this specific combination, but the theoretical basis for synergy is compelling
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