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Also, a phase III randomized placebo-controlled trial demonstrated that another compound protective against oxidative stress, dexpramipexole, did not improve motor function in ALS patients (Cudkowicz et al., 2013)

Both medications are contraindicated in pregnancyNSAIDs particularly after 20 weeks gestation, and Wegovy should not be used during pregnancy or breastfeeding

doi:10.1016/j.eclinm.2024.102920 Klausen MK, Jensen ME, Mller M, et al

However, many of the studies in the review were done using mice or rats, Pelitera says

Figure 1 The specific molecular mechanism against oxidative stress is closely related to the nuclear factor erythroid 2-related factor (Nrf2)/Hemoxygenase 1 (HO-1) pathway (21)

These medications help control blood sugar and promote weight loss