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Alternatively, introducing a refeed day or temporary caloric increase can reset metabolic adaptation and restore progress

Patients entered a 2-week, single-blind run-in treatment period on pre-mixed, long-acting, or intermediate-acting insulin, with or without metformin HCl (1500 mg per day)

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So where harm can happen is not having that whole system, that ecosystem, you know, approach for an individual on the flip side, where it can be so incredibly helpful

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