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A key difference between the two drugs is that Zepbound is a dual receptor agonist that works on both GLP-1 and gastric inhibitory polypeptide (GIP)
However, combining these medications may increase the risk of side effects, requiring close monitoring of blood glucose levels and overall health
Some of the most commonly prescribed drugs are liraglutide (Saxenda), which is usually used for weight management, semaglutide (Wegovy and Ozempic), which is useful for both weight loss and diabetes management, and dulaglutide (Trulicity), this is often used for diabetes but can also be used for weight control
It also slightly elevates the possibility of cancer with prolonged high doses
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In particular, combining 2-OHNA with other NAD + biosynthesis inhibitors like FK866 effectively kills NAPRT-proficient cancer cells resistant to single-agent treatments 217
