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it was studied by Novo Nordisk and later Helsinn Therapeutics, including a Phase II trial for postoperative ileus, but development was discontinued for lack of efficacy

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Following randomization, participants entered a six-month treatment period with either 2 g/day of oral L-C or placebo (cellulose), both given in divided doses in the morning (2 500 mg) and evening (2 500 mg)