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Similarly, some authors observed that metformin users had a lower clinical severity of TC at presentation and a longer disease free survival in metastatic patients (Jang et al., 2015), while other authors did not observe any difference in the risk of developing metastases when compared with non-treated patients (Noh et al., 2019)

845 Transcriptomic analyses of patients with intestinal I/R injury and mice showed that ferroptosis-related genes such as IL-6, CXCL2, HMOX1, GDF15, HSPA5, and TNFAIP3, may be hub genes in intestinal I/R injury

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