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Shortening the fatty acid chain length of rat ghrelin was reported to gradually increase the EC 50 (half maximal effective concentration) for receptor activation by 10-fold with hexanoyl (C6:0), 200-fold with butyryl (C4:0), and 500-fold with acetyl (C2:0) (Matsumoto et al., 2001)

Always consult a qualified healthcare provider before beginning any peptide therapy

The ferroptotic potential of CCW16 is reminiscent to the small molecule RSL3 that acts as a covalent inhibitor of GPX4 79

10.1038/mi.2014.35 8 ChenJ.XuF.RuanX.SunJ.ZhangY.ZhangH.et al (2023a)