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What started as a glucose-lowering mechanism is now a platform for treating obesity, metabolic dysfunction-associated steatohepatitis (MASH), cardiovascular disease, and potentially neurodegenerative conditions

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The MPC1 gene is located on chromosome 6q27 and is composed of 7 exons that generate seven alternatively spliced mRNAs encoding MPC1 isoform 1 (109 amino acids), MPC1 isoform 2 (66 amino acids), and MPC1 isoform 3 (70 amino acids)

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Synthetic peptide impurity profiling and quality-control study