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The most common side effectsnausea, constipation, and reduced appetitetypically decrease during the maintenance phase due to lower doses
Hypoglycemia Scores for patient perceptions of hypoglycemia were similar between orally administered semaglutide 7 and 14 mg compared with dulaglutide 0.75 mg at week 26 (change in scores from baseline 3.4 and 2.5, respectively, vs 3.1) and were not statistically different at week 52 (3.5 and 3.6 vs 0.5) (Fig
Patients with reduced GLP-1R sensitivity often need stronger or more continuous dosing to prevent rebound
N.BurroughsH.GorchakovR.GunterS
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