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The three-way comparison of semaglutide, tirzepatide, and retatrutide provides context for how single-agent retatrutide stacks up

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Guidelines typically call for engagement with intensive lifestyle interventions to address key influencers of cardiometabolic health and optimize weight loss and physiological improvement

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Retatrutide Retatrutide is a peptide therapy designed to aid in weight loss and metabolic health by targeting three key hormone receptors: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors

Patients were additionally required to have 1 of the following based on data from the 1-year baseline period or the index date: 1 International Classification of Diseases, Tenth Revision (ICD-10) diagnosis code or electronic medical record indicating overweight (BMI of 2529.9 kg/m) with 1 obesity-related complication (identified through ICD-10 diagnosis codes) or 1 ICD-10 diagnosis code or electronic medical record indicating obesity (BMI 30 kg/m 2