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Some clinical discussions suggest that GHRH analogs like Sermorelin may produce GH release patterns more similar to natural pulsatile secretion since they work through the endogenous pathway
Maintaining muscle is vital for keeping the metabolism active and supporting bone density
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Interestingly, a recent study examining the time-dependent effect of low IGF-1 levels on aging outcomes observed that a targeted reduction in liver-derived IGF-1 early (10 d or 5 mo) or later in life (15 mo) improved aspects of lifespan in females, though these effects were most pronounced when IGF-1 was reduced at 5 mo old 19
