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The clinical success of exenatide is based on its ability to effectively mimic incretin effects, its resistance to DPP-4, and its longer duration of action compared to native human GLP-1
These phenotypes included DNA methylation (N = 32,851) 24 , gene expression (N ranging from 174 to 29,621) 25,26,27 , alternative splicing events (N = 305) 28 and protein levels (N ranging from 35,329 to 35,431) 29,30,31,32,33,34,35,36,37,38 , which these variants were noted as molecular quantitative trait loci (QTLs)
Its also worth being careful with expectations: if your B12 levels are already normal, injections are unlikely to be a meaningful energy boost
This dual purpose, both therapeutic and pharmaceutical, makes it an elegant addition to the formulation
M., Cao, X