According to Bloomberg, a spokesperson from the Michigan insurer cited consideration of the drugs effectiveness, safety and cost in reaching this decision, but did not respond to a question about what the safety concerns were. 2 According to the BCBS Michigan provider alert itself, the decision was based on a number of factors, including research indicating weight loss success is significantly higher when medication is used in combination with lifestyle changes such as diet and exercise rather than on its own
Factors like water retention, sleep, protein intake, and activity all play a role
Ideally, look for a provider who prescribes both HRT and GLP-1 medications in their practice
In large RCTs, patients receiving semaglutide, 2.4mg, lost a mean of 6% of their weight by week 12 and 12% of their weight by week 28
Most patients start noticing appetite changes within the first week, with significant weight loss typically visible within 1-3 months
Stuck in a time of awkward moments and bad decisions