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Superior Clinical Results Phase 2 data showed up to 24.2% body weight reduction at 48 weeks surpassing both semaglutide and tirzepatide
The weight (and PCOS symptoms) often come back
Most side effects are transient and manageable with supportive measures, though awareness of typical onset patterns facilitates better treatment adherence and patient-provider communication
Growth hormone-releasing hormone
In selecting efficacious treatment for people with T2DM and risk of CVD, the ADA/EASD consensus statement notes that both SGLT2i and GLP-1 RA interventions may be appropriate, and recommend determining the existence of established CVD, or the probable risk of developing CVD or CKD
These effects typically diminish as patients adapt
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