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For a calculator-page article, the relevance is editorial and documentation-based: analytical claims should be tied to evidence, not calculator context

There were minimal microbiome differences between lean and obese controls, suggesting that diet composition and adiposity had limited effects

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Different research groups and funders have different priorities, ranging from more immediate protection against all variants of single species, such as SARS-CoV-2, to the long-term ambitious goal of protection against future pandemics