Genetic predisposition does not predict exact medication response, but may help personalize expectations and monitoring strategies
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Slivka A, Mytilineou C, Cohen G
The American College of Rheumatology guidelines emphasize weight loss as a core non-pharmacological intervention for overweight and obese patients with knee osteoarthritis, with evidence supporting that even modest weight reduction (5-10% of body weight) can produce clinically meaningful improvements in pain and function
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Instead of pointing fingers, its better to be productive and look for solutions