This is a fundamental biological reality of weight loss, not a failure of the GLP-1 drug itself whatsoever
The combined treatment reduced HbA1c to a greater degree considering it decreased by 2.2% with the combination of semaglutide and cagrilinide, 1.8% with semaglutide alone, and 0.9% with cagrilintide [2]
Its being studied for depression, OCD, addiction, and neurodegenerative diseases
Semaglutide, delayed gastric emptying, and intraoperative pulmonary aspiration: a case report
Orlistat causes different side effects related to its mechanism of reducing fat absorption: Oily spotting and flatulence Urgent bowel movements and faecal incontinence Oily or fatty stools These effects are typically worse when consuming high-fat meals and can be socially distressing
Coverage for diabetes is different