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The findings of the rapid and long-lasting antidepressant effects of LAC (which increases the expression of mGlu2, inhibitor of spontaneous glutamate release) supports the idea that targeting the glutamate system can lead to rapid antidepressant effects in agreement with the prior discovery of the antidepressant action of ketamine [48,49,50]

Therefore, we recommend starting with a lower dose and gradually adjusting it according to your needs and comfort

Agrati C, Sacchi A, Bordoni V, Cimini E, Notari S, Grassi G, et al

Tempol improves renal autoregulation and kidney function following Ischemia-Reperfusion injury in rats

Alterations of oligodendrocyte and myelin energy metabolism in multiple sclerosis

472 A high-iron diet significantly reduces SLC7A11 expression and GSH levels, and exacerbating cardiac injury and myocardial hypertrophy in cardiomyocyte-specific FTH knockout mice